Weekly Chest CasesArchive of Old Cases

Case No : 874 Date 2014-07-28

  • Courtesy of Yunhong Yoon, Ji-hyun Lee, Yun-hyeon Kim / Chonnam National University Hospital
  • Age/Sex 60 / M
  • Chief ComplaintCough, blood tinged sputum for 2 months, History of tuberculosis
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Diagnosis With Brief Discussion

Diagnosis
Diffuse large B-cell lymphoma associated chronic inflammation (Pyothorax-associated lymphoma)
Radiologic Findings
Initial chest radiogram and CT images show large amount of right pleural loculated fluid collection with calcified wall thickening and air-fluid level, which represent chronic empyema. Additionally, right pleura and wall of empyema show diffuse mild nodular thickening with enhancement. Thoracostomy was done.
After 6 weeks, chest radiogram and CT images shows aggravation of thickening and enhancement of right pleura and wall of empyema. VATS lung decortication was done and empyema peel biopsy was confirmed as diffuse large B-cell lymphoma, associated with chronic inflammation.
And PET-CT scan shows multiple hypermetabolic lesions along right pleura and empyema wall. The patient had history of tuberculous pleuritis in 1987. EBV VCA immunoglobuin G was positive.
Brief Review
Please refer to
Case 460,
References
Ueda T, Andreas C, Itami J, Miyakawa K, Fujimoto H, Ito H, Roos JE. Pyothorax-associated lymphoma: imaging findings. AJR 2010; 194:76-84
Keywords
Pleura, Malignant tumor, Lymphoma,

No. of Applicants : 73

▶ Correct Answer : 24/73,  32.9%
  • - The University of Tokyo Hospital , Japan Akifumi Hagiwara
  • - Niigata City General Hospital , Japan Takao Kiguchi
  • - Kyoto University , Japan Akihiko Sakata
  • - The University of Tokyo Hospital , Japan Takeyuki Watadani
  • - Department of Radiology, Sanggye Paik Hospital, Inje University College of Medicine , Korea (South) youngseon kim
  • - jaslok hospital & research centre mumbai , India JAINENDRA JAIN
  • - Chonnam National University Hospital , Korea (South) So yeon Ki
  • - Kobe City Medical Center General Hospital , Japan Yasuhisa Kurata
  • - Medical College Chest Hospital,Thrissur,Kerala , India Raveendran TK
  • - Asan medical center , Korea (South) Sang Young Oh
  • - Asan Medical Center, Ulsan University , Korea (South) Mi Young Kim
  • - Kizawa Memorial Hospital , Japan Yo Kaneko
  • - Shiga University of Medical Science , Japan Akitoshi Inoue
  • - , Korea (South) Chan Park
  • - IRSA La Rochelle , France Denis Chabassiere
  • - Onomichi municipal hospital , Japan Hirofumi Mifune
  • - Japanese national center hospital of neurology and psychiatry , Japan Kaoru Sumida
  • - ZIGONG TCM HOSPITAL OF CHINA , China Cao Cunyou
  • - Seirei Hamamatsu General Hospital , Japan Kenichi Mizuki
  • - Medicheck health care , Korea (South) Chae Lim
  • - Chia Nan University of Pharmacy and Science ,Taiwan, R.O.C. , Taiwan Jun Jun Yeh
  • - Gifu Central Hospital , Japan Haruo Watanabe
  • - Northern Yokohama Showa university , Japan Kota Watanabe
  • - SNUH , Korea (South) Eui Jin Hwang
▶ Correct Answer as Differential Diagnosis : 13/73,  17.8%
  • - NIMS, HYDERABAD , India bhaskar kakarla
  • - Yokohama-asahi-chuo-general hospital , Japan Kyoko Nagai
  • - Oita University, Faculty of Medicine , Japan Fumito Okada
  • - Seoul National University Hospital , Korea (South) Sang Min Lee
  • - The University of Tokyo Hospital , Japan Toshihiro Furuta
  • - Kanto Rosai Hospital , Japan tomoko sako
  • - IRSA LA ROCHELLE , France, Metropolitan BIGOT
  • - Niigata University , Japan Atsushi Uehara
  • - Onomichi Municipal Hospital , Japan Yoshihisa Masaoka
  • - Pneumologia Universitaria, Policlinico di Bari , Italy Mario Damiani
  • - Nagasaki University Hospital, Department of Pathology , Japan TOMONORI TANAKA
  • - Onomichi municipal hospital , Japan Toshiyuki Komaki
  • - Private sector , Greece Vasilios Tzilas
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